Preparation of Bio-Sensor with Hybrid Nanofibers of Chitosan/ Functional Carbon Nanotubes for the Sensing of Nicotine

Document Type : Original Article

Authors

1 Department of Biomedical Engineering, South Tehran Branch, Islamic Azad University, P.O. Box: 1955764955:1,2,3, Tehran, Iran

2 Department of Biomedical Engineering, South Tehran Branch, Islamic Azad University, Tehran Iran

Abstract

In this paper, Nicotine (NIC) was detected by cyclic voltammetry (CV) using a modified glassy carbon electrode (GC). To do this, the surface of the GC electrode was modified by hybrid Nanofiber obtained from electrospinning method. Hybrid nanofibers were produced through the dispersion of carboxylated Multi-walled carbon nanotube (MWCNT-COOH) as an inorganic component in the CS polymer matrix as an organic component. The nanofibers showed unique morpHology and high surface area value. With the increase of functionalized carbon nanotube content in the nanofibers, the mean pore diameter and the average nanofiber diameter increased. The electrochemical properties of nanofibers toward the sensing of NIC were investigated by cyclic voltammetry method. NIC was irreversibly reduced with the use of CS/MWCNT-COOH electrode, a controlled process with 2 protons and 2 electrons. An oxidation signal at lower potential with higher current was obtained for nicotine with the use of polymer-modified electrode compared to glassy carbon electrode.

Keywords

References

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